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Oxygenation can be determined by a patient history, lab testing and physical exam, and can be improved by making changes to environment, posture, lifestyle and through supplemental nutrition
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A person addicted to this drug and misuses the dosage may become very sleepy, have small pupils and have trouble breathing if they are using the medication just to get high.
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Auto refill is seen as a way to improve compliance, Harlam says
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